2012
Picard, D. (2012). Preface to Hsp90. Biochim. Biophys. Acta 1823, 605-606. [DOI]
2011
Echeverría, P. C., Bernthaler, A., Dupuis, P., Mayer, B., and Picard, D. (2011). An interaction network predicted from public data as a discovery tool: application to the Hsp90 molecular chaperone machine. PLoS ONE 6, e26044 [Open Access]
Digard, P., Ge, X., Rameix-Welti, M.-A., Gault, E., Chase, G., dos Santos Afonso, E., Picard, D., Schwemmle, M., and Naffakh, N. (2011). Influenza virus infection induces the nuclear relocalization of the Hsp90 co-chaperone p23 and inhibits the glucocorticoid receptor response. PLoS ONE 6, e23368. [Open Access]
Echeverria, P. C., Forafonov, F., Pandey, D. P., Mühlebach, G., and Picard, D. (2011). Detection of changes in gene regulatory patterns, elicited by perturbations of the Hsp90 molecular chaperone complex, by visualizing multiple experiments with an animation. BioData Mining 4, 15. [Open Access]
Lappano, R., Recchia, A. G., De Francesco, E. M., Angelone, T., Cerra, M. C., Picard, D., and Maggiolini, M. (2011). The cholesterol metabolite 25-hydroxycholesterol activates estrogen receptor α-mediated signaling in cancer cells and in cardiomyocytes. PLoS ONE 6, e16631.
[PLoSOne]
2010
Grad, I., Cederroth, C. R., Walicki, J., Grey, C., Barluenga, S., Winssinger, N., De Massy, B., Nef, S., and Picard, D. (2010). The molecular chaperone Hsp90α is required for meiotic progression of spermatocytes beyond pachytene in the mouse. PLoS ONE 5, e15770.
[PLoS One]Pandey, D. P., and Picard, D. (2010). Multidirectional interplay between nuclear receptors and microRNAs. Curr. Opin. Pharmacol. 10, 637-642.
[Pubmed]Carascossa, S.*, Dudek, P.*, Cenni, B., Briand, P.-A., and Picard, D. (2010). CARM1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor α by cAMP. Genes Dev. 24, 708-719.
[Genes Dev]Echeverría, P. C., and Picard, D. (2010). Molecular chaperones, essential partners of steroid hormone receptors for activity and mobility. Biochim. Biophys. Acta 1803, 641-649
[Pubmed]Maggiolini, M., and Picard, D. (2010). The unfolding stories of GPR30, a new membrane-bound estrogen receptor. J. Endocrinol. 204, 105-114.
[Pubmed]
2009
Pandey, D.P., and Picard, D. (2009). miR-22 inhibits estrogen signaling by directly targeting the estrogen receptor α mRNA. Mol. Cell. Biol. 29, 3783-3790.
[MCB]Wider, D., Péli-Gulli, M.-P., Briand, P.-A., Tatu, U., and Picard, D. (2009). The complementation of yeast with human or Plasmodium falciparum Hsp90 confers differential inhibitor sensitivities. Mol. Biochem. Parasitol. 164, 147-152.
[doi]Pandey, D. P., Lappano, R., Albanito, L., Madeo, A., Maggiolini, M., and Picard, D. (2009). Estrogenic GPR30 signaling induces proliferation and migration of breast cancer cells through CTGF. EMBO J. 28, 523-532.
[Pubmed]
2008
Picard, D. (2008). A stress protein interface of innate immunity. EMBO Rep. 9, 1193-1195.
[Pubmed]Lev, A., Takeda, K., Zanker, D., Maynard, J. C., Dimberu, P., Waffarn, E., Gibbs, J., Netzer, N., Princiotta, M. F., Neckers, L., Picard, D., Nicchitta, C. V., Chen, W., Reiter, Y., Bennink, J. R., and Yewdell, J. W. (2008). The exception that reinforces the rule: crosspriming by cytosolic peptides that escape degradation. Immunity 28, 787-798.
[Pubmed]Albanito, L., Sisci, D., Aquila, S., Brunelli, E., Vivacqua, A., Madeo, A., Lappano, R., Pandey, D. P., Picard, D., Mauro, L., Andò, S., and Maggiolini, M. (2008). EGF induces GPR30 expression in estrogen receptor-negative breast cancer cells. Endocrinology 149, 3799-3808.
[Pubmed]Forafonov, F., Toogun, O. A., Grad, I., Suslova, E., Freeman, B. C., and Picard, D. (2008). p23/Sba1p protects against Hsp90 inhibitors independently of its intrinsic chaperone activity. Mol. Cell. Biol. 28, 3446-3456.
[Pubmed]Dudek, P. and Picard, D. (2008). Genomics of signaling crosstalk of estrogen receptor α in breast cancer cells. PLoS One 3, e1859.
[PLoS One]
2007
Grad, I., and Picard, D. (2007). The glucocorticoid responses are shaped by molecular chaperones. Mol. Cell. Endocrinol. 275, 2-12.
[Pubmed]Mehenni, H., Resta, N., Guanti, G., Mota-Vieira, L., Lerner, A., Peyman, M., Chong, K. A., Aissa, L., Ince, A., Cosme, A., Costanza, M. C., Rossier, C., Radhakrishna, U., Burt, R. W., and Picard, D. (2007). Molecular and clinical characteristics in 46 families affected with Peutz-Jeghers syndrome. Dig. Dis. Sci.52, 1924-1933.
[Pubmed]
2006
Grad, I., McKee, T. A., Ludwig, S. M., Hoyle, G. W., Ruiz, P., Wurst, W., Floss, T., Miller III, C. A., and Picard, D. (2006). The Hsp90 co-chaperone p23 is essential for perinatal survival. Mol. Cell. Biol. 26, 8976-8983.
[Pubmed]Picard, D., Suslova, E., and Briand, P.-A. (2006). 2-color photobleaching experiments reveal distinct intracellular dynamics of two components of the Hsp90 complex. Exp. Cell Res. 312, 3949-3958.
[Pubmed]Vivacqua, A., Bonofiglio, D., Albanito, L., Madeo, A., Rago, V., Carpino, A., Musti, A. M., Picard, D., Andò, S., and Maggiolini, M. (2006). 17β-estradiol, genistein and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the G protein-coupled receptor GPR30. Mol. Pharmacol. 70, 1414-1423.
[Pubmed]Picard, D. (2006). Chaperoning steroid hormone action. Trends Endocrinol. Metab. 17, 229-235.
[Pubmed]Gburcik, V., and Picard, D. (2006). The cell-specific activity of the estrogen receptor α may be fine-tuned by phosphorylation-induced structural gymnastics. Nuclear Receptor Signaling 4, doi:10.1621/nrs.04005.
Online accessPhelps, C.*, Gburcik, V.*, Suslova, E.*, Dudek, P.*, Forafonov, F.*, Bot, N., MacLean, M., Fagan, R. J., and Picard, D. (2006). Fungi and animals may share a common ancestor to nuclear receptors. Proc. Natl. Acad. Sci. USA 103, 7077-7081.
(* these authors contributed equally)
[Pubmed]Picard, D. (2006). Intracellular dynamics of the Hsp90 co-chaperone p23 is dictated by Hsp90. Exp. Cell Res. 312, 198-204.
[Pubmed]Vivacqua, A., Bonofiglio, D., Recchia, A. G., Musti, A. M., Picard, D., Andò, S., and Maggiolini, M. (2006). The G protein-coupled receptor GPR30 mediates the proliferative effects induced by 17β-estradiol and hydroxytamoxifen in endometrial cancer cells. Mol. Endocrinol. 20, 631-646.
[Pubmed]
2005
Gburcik, V., Bot, N., Maggiolini, M., and Picard, D. (2005). SPBP is a phosphoserine-specific repressor of estrogen receptor α. Mol. Cell. Biol. 25, 3421-3430.
[Pubmed]MacLean, M. J., Martínez Llordella, M., Bot, N., and Picard, D. (2005). A yeast-based assay reveals a functional defect of the Q488H polymorphism in human Hsp90α. Biochem. Biophys. Res. Commun. 337, 133-137.
[Pubmed]Mehenni, H., Lin-Marq, N., Buchet-Poyau, K., Reymond, A., Collart, M. A., Picard, D.*, and Antonarakis, S. E.* (2005). LKB1 interacts with and phosphorylates PTEN - a functional link between two proteins involved in cancer predisposing syndromes. Hum. Mol. Genet. 14, 2209-2219. (* these authors contributed equally)
[Pubmed]Leskinen, P., Michelini, E., Picard, D., Karp, M., and Virta, M. (2005). Bioluminescent yeast assays for detecting estrogenic and androgenic activity in different matrices. Chemosphere 61, 259-266.
[Pubmed]
2004
Donzé, O., Dudek, P., and Picard, D. (2004). siRNA production by in vitro transcription. In Gene Silencing by RNA Interference: Technology and Application, M. Sohail, ed. (CRC Press LLC), pp. 59-72.
Picard, D. (2004). Hsp90 invades the outside. Nat. Cell Biol. 6, 479-480.
[Pubmed]Dudek, P., and Picard, D. (2004). TROD: T7 RNAi Oligo Designer. Nucleic Acids Res. 32, W121-123.
[Pubmed]Maggiolini, M., Recchia, A. G., Carpino, A., Vivacqua, A., Fasanella, G., Rago, V., Pezzi, V., Briand, P.-A., Picard, D., and Andò, S. (2004). Estrogen receptor β is required for androgen-stimulated proliferation of LNCaP prostate cancer cells. J. Mol. Endocrinol. 32, 777-791.
[Pubmed]Picard, C., and Picard, D. (2004). A web application to manage a database for liquid nitrogen tanks. Immunol. Cell Biol. 82, 257-259.
[Pubmed]Donzé, O., Deng, J., Curran, J., Sladek, R., Picard, D.*, and Sonenberg, N. * (2004). The interferon-induced protein kinase PKR: a molecular clock that sequentially activates survival and death programs. EMBO J. 23, 564-571. (* these authors contributed equally)
[Pubmed]Maggiolini, M., Vivacqua, A., Fasanella, G., Recchia, A. G., Sisci, D., Pezzi, V., Montanaro, D., Musti, A. M., Picard, D., and Andò, S. (2004). The G protein-coupled receptor GPR30 mediates c-fos up-regulation by 17β-estradiol and phytoestrogens in breast cancer cells. J. Biol. Chem. 279, 27009-27016.
[Pubmed]Pinto, B., Picard, D., and Reali, D. (2004). A recombinant yeast strain as a short term bioassay to assess estrogen-like activity of xenobiotics. Ann. Ig. 16, 579-585.
[Pubmed]
2003
Picard, D. (2003). SCOPE/IUPAC project on environmental implications of endocrine active substances: Molecular mechanisms of cross-talk between growth factors and nuclear receptor signaling. Pure Appl. Chem. 75, 1743-1756.
Riggs, D. L., Roberts, P. J., Chirillo, S. C., Cheung-Flynn, J., Prapapanich, V., Ratajczak, T., Gaber, R., Picard, D., and Smith, D. F. (2003). The Hsp90-binding peptidylprolyl isomerase FKBP52 potentiates glucocorticoid signaling in vivo. EMBO J. 22, 1158-1167.
[Pubmed]MacLean, M., and Picard, D. (2003). Cdc37 goes beyond Hsp90 and kinases. Cell Stress Chaperones 8, 114-119.
[Pubmed]
2002
Maggiolini, M., Bonofiglio, D., Pezzi, V., Carpino, A., Marsico, S., Rago, V., Vivacqua, A., Picard, D., and Andò, S. (2002). Aromatase overexpression enhances the stimulatory effects of adrenal androgens on MCF7 breast cancer cells. Mol. Cell. Endocrinol. 193, 13-18.
[Pubmed]Abbas-Terki, T., Briand, P.-A., Donzé, O., and Picard, D. (2002). The Hsp90 co-chaperones Cdc37 and Sti1 interact physically and genetically. Biol. Chem. 383, 1335-1342.
[Pubmed]Foray, N., Marot, D., Randrianarison, V., Dalla Venezia, N., Picard, D., Perricaudet, M., Favaudon, V., and Jeggo, P. (2002). Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation. Mol. Cell. Biol. 22, 4020-4032.
[Pubmed]Donzé, O., and Picard, D. (2002). RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. Nucleic Acids Res. 30, e46.
[Pubmed]Picard, D. (2002). Heat-shock protein 90, a chaperone for folding and regulation. Cell. Mol. Life Sci. 59, 1640-1648.
[Pubmed]
2001
Maggiolini, M., Carpino, A., Bonofiglio, D., Pezzi, V., Rago, V., Marsico, S., Picard, D., and Andò, S. (2001). The direct proliferative stimulus of dehydroepiandrosterone on MCF7 breast cancer cells is potentiated by overexpression of aromatase. Mol. Cell. Endocrinol. 184, 163-171.
[Pubmed]Maggiolini, M., Bonofiglio, D., Marsico, S., Panno, M. L., Cenni, B., Picard, D., and Andò, S. (2001). Estrogen receptor α mediates the proliferative but not the cytotoxic dose-dependent effects of two major phytoestrogens on human breast cancer cells. Mol. Pharmacol. 60, 595-602.
[Pubmed]Abbas-Terki, T., Donzé, O., Briand, P.-A., and Picard, D. (2001). Hsp104 interacts with Hsp90 cochaperones in respiring yeast. Mol. Cell. Biol. 21, 7569-7575.
[Pubmed]Donzé, O., Abbas-Terki, T., and Picard, D. (2001). The Hsp90 chaperone complex is both a facilitator and a repressor of the dsRNA-dependent kinase PKR. EMBO J. 20, 3771-3780.
[Pubmed]
2000
Picard, D. (2000). Posttranslational regulation of proteins by fusions to steroid-binding domains. Methods Enzymol. 327, 385-401.
[Pubmed]Scheidegger, K. J., Cenni, B., Picard, D., and Delafontaine, P. (2000). Estradiol decreases IGF-1 and IGF-1 receptor expression in rat aortic smooth muscle cells: Mechanisms for its atheroprotective effects. J. Biol. Chem. 275, 38921-38928.
[Pubmed]Abbas-Terki, T., Donzé, O., and Picard, D. (2000). The molecular chaperone Cdc37 is required for Ste11 function and pheromone-induced cell cycle arrest. FEBS Lett. 467, 111-116.
[Pubmed]
1999
Maggiolini, M., Donzé, O., Jeannin, E., Andò, S., and Picard, D. (1999). Adrenal androgens stimulate the proliferation of breast cancer cells as direct activators of estrogen receptor α. Cancer Res. 59, 4864-4869.
[Pubmed]Maggiolini, M., Donzé, O., and Picard, D. (1999). A non-radioactive method for inexpensive quantitative RT-PCR. Biol. Chem. 380, 695-697.
[Pubmed]Picard, D., ed. (1999). Nuclear receptors: a practical approach. Vol. 207 (Oxford: Oxford University Press).
Cenni, B., and Picard, D. (1999). Ligand-independent activation of steroid receptors: new roles for old players. Trends Endocrinol. Metab. 10, 41-46.
[Pubmed]Picard, D. (1999). Regulation of heterologous proteins by fusion to a hormone binding domain. In Nuclear receptors: a practical approach. D. Picard, ed., Vol. 207 (Oxford: Oxford University Press), pp. 261-274.
Donzé, O., and Picard, D. (1999). Hsp90 binds and regulates Gcn2, the ligand-inducible kinase of the α subunit of eukaryotic translation initiation factor 2. Mol. Cell. Biol. 19, 8422-8432.
[Pubmed]Abbas-Terki, T., and Picard, D. (1999). α-complemented β-galactosidase. An in vivo model substrate for the molecular chaperone heat-shock protein 90 in yeast. Eur. J. Biochem. 266, 517-523.
[Pubmed]Liu, J. W., Jeannin, E., and Picard, D. (1999). The anti-estrogen hydroxytamoxifen is a potent antagonist in a novel yeast system. Biol. Chem. 380, 1341–1345.
[Pubmed]Cenni, B., and Picard, D. (1999). Two compounds commonly used for phospholipase C inhibition activate the nuclear estrogen receptors. Biochem. Biophys. Res. Commun. 261, 340-344.
[Pubmed]Balmelli-Gallacchi, P., Schoumacher, F., Liu, J. W., Eppenberger, U., Müller, H., and Picard, D. (1999). A yeast-based bioassay for the determination of functional and non-functional estrogen receptors. Nucleic Acids Res. 27, 1875-1881.
[Pubmed]